NOVEL INFECTIVITY-ENHANCED ONCOLYTIC ADENOVIRUS WITH A CAPSID-INCORPORATED DUAL-IMAGING MOIETY FOR MONITORING VIROTHERAPY IN OVARIAN CANCER

Novel Infectivity-Enhanced Oncolytic Adenovirus with a Capsid-Incorporated Dual-Imaging Moiety for Monitoring Virotherapy in Ovarian Cancer

We sought to develop a cancer-targeted, infectivity-enhanced oncolytic adenovirus that embodies a capsid-labeling fusion for non-invasive dual-modality imaging of ovarian cancer virotherapy.A functional fusion protein composed of fluorescent and nuclear imaging tags was genetically incorporated into the capsid of an infectivity-enhanced conditional

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Parametric updates in parametric timed automata

We introduce a new class of Parametric Timed Automata (PTAs) where we allow clocks to be compared to parameters in guards, as in classic PTAs, but also to be updated to parameters.We focus here on the EF-emptiness problem: "is the set of parameter valuations for which some given location is reachable in the nacrack.com instantiated timed automaton

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Undergraduate exposure to patient presentations on the acute medical placement: a prospective study in a London teaching hospital

Objectives To identify the availability and variability of learning opportunities through patient presentations on an acute medical placement at a teaching hospital.Design A prospective study evaluating all acute admissions to the Acute Medical Unit over 14 days (336 hours).Clinical presentations and the day and time of admission were recorded and

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